2-Methyl-N-pyridin-3-yl-5-(3-trifluoromethyl-benzoylamino)-benzamide

• 常用名: 2-Methyl-N-pyridin-3-yl-5-(3-trifluoromethyl-benzoylamino)-benzamide
• 英文名: 2-Methyl-N-pyridin-3-yl-5-(3-trifluoromethyl-benzoylamino)-benzamide
• CAS号: 896157-09-8
• 分子量: 399.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₁₆F₃N₃O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-Methyl-N-pyridin-3-yl-5-(3-trifluoromethyl-benzoylamino)-benzamide

物理化学性质

• 分子式: C₂₁H₁₆F₃N₃O₂
• 分子量: 399.4
• InChIKey: PJHDLAYUOWOWCS-UHFFFAOYSA-N
• SMILES: Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1C(=O)Nc1cccnc1

靶点实验

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实验名称：Inhibition of full length His-tagged human B-Raf V600E mutant expressed in insect cel... 来源：ChEMBL 靶标：Serine/threonine-protein kinase B-raf External Id：CHEMBL947762

实验名称：Inhibition of p-ERK level in human COLO205 cells after 75 mins by crystal violet stai... 来源：ChEMBL 靶标：COLO 205 External Id：CHEMBL947763

实验名称：Volume of distribution at steady state in rat at 3 mg/kg, iv and 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL980058

实验名称：Clearance in rat at 3 mg/kg, iv and 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL980057

实验名称：Half life in rat at 3 mg/kg, iv and 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL980059

实验名称：Inhibition of CSF1R 来源：ChEMBL 靶标：Macrophage colony-stimulating factor 1 receptor External Id：CHEMBL980054

实验名称：Bioavailability in rat at 3 mg/kg, iv and 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL980056

实验名称：Antiproliferative activity against mouse 3T3 cells expressing human CSF1R after 72 hr... 来源：ChEMBL 靶标：NIH3T3 External Id：CHEMBL980055

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