3-Pyrrolidinecarboxylic acid, 1-[(2R)-[(1-amino-6-isoquinolinyl)amino](4-fluoro-3-methoxyphenyl)acetyl]-2-[2-(ethylsulfonyl)phenyl]-, (2R,3S)

• 常用名: 3-Pyrrolidinecarboxylic acid, 1-[(2R)-[(1-amino-6-isoquinolinyl)amino](4-fluoro-3-methoxyphenyl)acetyl]-2-[2-(ethylsulfonyl)phenyl]-, (2R,3S)
• 英文名: 3-Pyrrolidinecarboxylic acid, 1-[(2R)-[(1-amino-6-isoquinolinyl)amino](4-fluoro-3-methoxyphenyl)acetyl]-2-[2-(ethylsulfonyl)phenyl]-, (2R,3S)
• CAS号: 900173-62-8
• 分子量: 606.7
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₁H₃₁FN₄O₆S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-Pyrrolidinecarboxylic acid, 1-[(2R)-[(1-amino-6-isoquinolinyl)amino](4-fluoro-3-methoxyphenyl)acetyl]-2-[2-(ethylsulfonyl)phenyl]-, (2R,3S)

物理化学性质

• 分子式: C₃₁H₃₁FN₄O₆S
• 分子量: 606.7
• InChIKey: IZSJEKWHRIABKB-LBNPDIFZSA-N
• SMILES: CCS(=O)(=O)c1ccccc1C1C(C(=O)O)CCN1C(=O)C(Nc1ccc2c(N)nccc2c1)c1ccc(F)c(OC)c1

靶点实验

查看更多实验

实验名称：Anticoagulant activity in F7-deficient human plasma assessed as concentration require... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL3116754

实验名称：Selectivity ratio of Ki for thrombin (unknown origin) to Ki for human full length tis... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3116755

实验名称：Selectivity ratio of Ki for F11A (unknown origin) to Ki for human full length tissue ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3116756

实验名称：Permeability of the compound after 4 hrs by PAMPA 来源：ChEMBL 靶标：N/A External Id：CHEMBL3116757

实验名称：Binding affinity to human full length tissue factor/F7a using S-2288 as substrate pre... 来源：ChEMBL 靶标：Tissue factor External Id：CHEMBL3116761

实验名称：Selectivity ratio of Ki for F10A (unknown origin) to Ki for human full length tissue ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3116763

实验名称：Half life in dog at 0.2 mg/kg, iv 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3119291

实验名称：Volume of distribution at steady state in dog at 0.2 mg/kg, iv 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3119292

实验名称：Clearance in dog at 0.2 mg/kg, iv 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3119293

实验名称：Selectivity ratio of Ki for activated protein C (unknown origin) to Ki for human full... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3119294

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