4-(4-氟苯基)-7-[[[5-[(1S)-1-羟基-1-(三氟甲基)丙基]-1,3,4-恶二唑-2-基]氨基]甲基]-2H-1-苯并吡喃-2-酮

• 常用名: 4-(4-氟苯基)-7-[[[5-[(1S)-1-羟基-1-(三氟甲基)丙基]-1,3,4-恶二唑-2-基]氨基]甲基]-2H-1-苯并吡喃-2-酮
• 英文名: 4-(4-fluorophenyl)-7-[[[5-[(2S)-1,1,1-trifluoro-2-hydroxybutan-2-yl]-1,3,4-oxadiazol-2-yl]amino]methyl]chromen-2-one
• CAS号: 910656-27-8
• 分子量: 463.38200
• 密度: 1.478g/cm3
• 沸点: N/A
• 分子式: C₂₂H₁₇F₄N₃O₄
• 熔点: N/A
• 闪点: N/A

名称

• 中文名: 4-(4-氟苯基)-7-[[[5-[(1S)-1-羟基-1-(三氟甲基)丙基]-1,3,4-恶二唑-2-基]氨基]甲基]-2H-1-苯并吡喃-2-酮
• 英文名: 4-(4-fluorophenyl)-7-[[[5-[(2S)-1,1,1-trifluoro-2-hydroxybutan-2-yl]-1,3,4-oxadiazol-2-yl]amino]methyl]chromen-2-one

物理化学性质

• 密度: 1.478g/cm3
• 分子式: C₂₂H₁₇F₄N₃O₄
• 分子量: 463.38200
• 精确质量: 463.11600
• PSA: 104.62000
• LogP: 4.17600
• InChIKey: MAOIDRRXRLYJNV-NRFANRHFSA-N
• SMILES: CCC(O)(c1nnc(NCc2ccc3c(-c4ccc(F)cc4)cc(=O)oc3c2)o1)C(F)(F)F

靶点实验

查看更多实验

实验名称：Drug metabolism in NADPH fortified rat liver microsomes assessed as N-((4-(4-fluoroph... 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3530466

实验名称：Activity of rat recombinant CYP3A1 expressed in baculovirus-infected insect cells ass... 来源：ChEMBL 靶标：Cytochrome P450 3A1 External Id：CHEMBL3530295

实验名称：Activity of rat recombinant CYP3A2 expressed in baculovirus-infected insect cells ass... 来源：ChEMBL 靶标：Cytochrome P450 3A2 External Id：CHEMBL3530296

实验名称：Activity of rat recombinant CYP1A1 expressed in baculovirus-infected insect cells ass... 来源：ChEMBL 靶标：Cytochrome P450 1A1 External Id：CHEMBL3530293

实验名称：Activity of rat recombinant CYP1A2 expressed in baculovirus-infected insect cells ass... 来源：ChEMBL 靶标：Cytochrome P450 1A2 External Id：CHEMBL3530294

实验名称：Drug metabolism in rat urine assessed as N-((4-(4-fluorophenyl)-2-oxochroman-7-yl)met... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3540946

实验名称：Inhibition of 5-LOX (unknown origin) 来源：ChEMBL 靶标：Polyunsaturated fatty acid 5-lipoxygenase External Id：CHEMBL4152533

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英文别名

• setileuton