2-methyl-N-{4-methyl-3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)carbamoyl]phenyl}-3-(trifluoromethyl)benzamide

• 常用名: 2-methyl-N-{4-methyl-3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)carbamoyl]phenyl}-3-(trifluoromethyl)benzamide
• 英文名: 2-methyl-N-{4-methyl-3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)carbamoyl]phenyl}-3-(trifluoromethyl)benzamide
• CAS号: 925897-25-2
• 分子量: 603.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₂H₃₂F₃N₇O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-methyl-N-{4-methyl-3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)carbamoyl]phenyl}-3-(trifluoromethyl)benzamide

物理化学性质

• 分子式: C₃₂H₃₂F₃N₇O₂
• 分子量: 603.6
• InChIKey: YNJXLRWECIJSPA-UHFFFAOYSA-N
• SMILES: CC1=C(C=C(C=C1)NC(=O)C2=C(C(=CC=C2)C(F)(F)F)C)C(=O)NC3=CN=C(N=C3)NC4=CC=C(C=C4)N5CCN(CC5)C

靶点实验

查看更多实验

实验名称：Inhibition of T cell activation in human peripheral blood lymphocytes by mixed lympho... 来源：ChEMBL 靶标：Lymphocyte External Id：CHEMBL951936

实验名称：Inhibition of Tie2 by HTRF assay 来源：ChEMBL 靶标：Angiopoietin-1 receptor External Id：CHEMBL951932

实验名称：Inhibition of KDR by HTRF assay 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL951933

实验名称：Inhibition of p38alpha by HTRF assay 来源：ChEMBL 靶标：Mitogen-activated protein kinase 14 External Id：CHEMBL951934

实验名称：Inhibition of Jak3 by HTRF assay 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK3 External Id：CHEMBL951935

实验名称：HTRF Kinase Inhibition Assay from Article 10.1021/jm7010996: "Structure-guided design... 来源：BindingDB 靶标：N/A External Id：BindingDB_2959_1

实验名称：Selectivity ratio of IC50 for IL2 production to IC50 for TNFalpha production in human... 来源：ChEMBL 靶标：Blood External Id：CHEMBL951107

实验名称：Volume of distribution at steady state in Sprague-Dawley rat at 0.5 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL951112

实验名称：Half life in Sprague-Dawley rat at 0.5 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL951113

实验名称：AUC (0 to infinity) in Sprague-Dawley rat at 2 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL951114

共17条，当前第1页，共2页

1

2