(4-Cyclopropyl-1-piperazinyl)[4-[(4-fluoro-1-piperidinyl)methyl]phenyl]methanone

• 常用名: (4-Cyclopropyl-1-piperazinyl)[4-[(4-fluoro-1-piperidinyl)methyl]phenyl]methanone
• 英文名: (4-Cyclopropyl-1-piperazinyl)[4-[(4-fluoro-1-piperidinyl)methyl]phenyl]methanone
• CAS号: 929622-11-7
• 分子量: 345.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₈FN₃O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (4-Cyclopropyl-1-piperazinyl)[4-[(4-fluoro-1-piperidinyl)methyl]phenyl]methanone

物理化学性质

• 分子式: C₂₀H₂₈FN₃O
• 分子量: 345.5
• InChIKey: MGOGCSPDEHKPJR-UHFFFAOYSA-N
• SMILES: O=C(c1ccc(CN2CCC(F)CC2)cc1)N1CCN(C2CC2)CC1

靶点实验

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实验名称：Metabolic stability in Sprague-Dawley rat liver microsomes assessed as compound remai... 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3578411

实验名称：Ex vivo histamine H3 receptor occupancy in Sprague-Dawley rat striatum at 3 mg/kg, po... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3578424

实验名称：Apparent permeability across apical to basolateral side in human Caco2 cells at 10 uM... 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL3578414

实验名称：Apparent permeability across basolateral to apical side in human Caco2 cells at 10 uM... 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL3578415

实验名称：Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM ... 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3578412

实验名称：Half life in Sprague-Dawley rat at 1 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3578418

实验名称：Oral bioavailability in Sprague-Dawley rat at 10 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3578419

实验名称：Clearance in Sprague-Dawley rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3578416

实验名称：Volume of distribution at steady state in Sprague-Dawley rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3578417

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