4-[(2S)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]but anoic acid

• 常用名: 4-[(2S)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]but anoic acid
• 英文名: 4-[(2S)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]but anoic acid
• CAS号: 929916-05-2
• 分子量: 389.87300
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₄ClNO₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-[(2S)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]but anoic acid

物理化学性质

• 分子式: C₂₁H₂₄ClNO₄
• 分子量: 389.87300
• 精确质量: 389.13900
• PSA: 59.00000
• LogP: 4.77820
• InChIKey: PVCTYSQBVIGZRU-KRWDZBQOSA-N
• SMILES: O=C(O)CCCN1CCCC1COc1ccc(Oc2ccc(Cl)cc2)cc1

靶点实验

查看更多实验

实验名称：Oral bioavailability in dog at 10 mg/kg 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL1041838

实验名称：Volume of distribution in dog at 10 mg/kg, iv 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL1041839

实验名称：Human Leukotriene A4 hydrolase (Hydrolases) 来源：IUPHAR-DB 靶标：Leukotriene A4 hydrolase (Hydrolases) [Homo sapiens] External Id：1395_Human

实验名称：AUC (0 to infinity) in dog at 10 mg/kg, po 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL1041837

实验名称：Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) e... 来源：ChEMBL 靶标：Leukotriene A-4 hydrolase External Id：CHEMBL4834692

实验名称：Half life in dog at 10 mg/kg, po 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL1041835

实验名称：Inhibition of LTA4H in human PBMC assessed as reduction of calcium ionophore A23187-s... 来源：ChEMBL 靶标：Leukotriene A-4 hydrolase External Id：CHEMBL4834691

实验名称：Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A... 来源：ChEMBL 靶标：Leukotriene A-4 hydrolase External Id：CHEMBL4834690

实验名称：Clearance in monkey at 10 mg/kg, iv 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL1042635

实验名称：Oral bioavailability in monkey at 10 mg/kg 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL1042633

共36条，当前第1页，共4页

1

2

3

4

英文别名

• Vilanterol
• vilanterolum