Bucladesine钙盐

更新时间：2026-07-01 14:16:47

Bucladesine钙盐结构式	常用名	Bucladesine钙盐	英文名	Bucladesine (calcium salt)
	CAS号	938448-87-4	分子量	976.8
	密度	N/A	沸点	N/A
	分子式	C₃₆H₄₆CaN₁₀O₁₆P₂	熔点	N/A
	MSDS	N/A	闪点	N/A

Bucladesine钙盐用途

Bucladesine钙盐(DC2797钙盐)是PKA选择性且细胞可通透激动剂。

中文名	Bucladesine钙盐
英文名	Bucladesine calcium salt
英文别名	更多

描述	Bucladesine钙盐(DC2797钙盐)是PKA选择性且细胞可通透激动剂。
相关类别	信号通路 >> 蛋白酪氨酸激酶 >> PKA 信号通路 >> 干细胞及 Wnt 通路 >> PKA 研究领域 >> 其他
参考文献	[1]. Sharifzadeh, M., et al., Post-training intrahippocampal infusion of nicotine-bucladesine combination causes a synergistic enhancement effect on spatial memory retention in rats. Eur J Pharmacol, 2007. 562(3): p. 212-20. [2]. Azami, K., et al., The quantitative evaluation of cholinergic markers in spatial memory improvement induced by nicotine-bucladesine combination in rats. Eur J Pharmacol, 2010. 636(1-3): p. 102-7. [3]. Mafune, E., M. Takahashi, and N. Takasugi, Effect of vehicles on percutaneous absorption of bucladesine (dibutyryl cyclic AMP) in normal and damaged rat skin. Biol Pharm Bull, 1995. 18(11): p. 1539-43. [4]. Rundfeldt, C., et al., The stable cyclic adenosine monophosphate analogue, dibutyryl cyclo-adenosine monophosphate (bucladesine), is active in a model of acute skin inflammation. Arch Dermatol Res, 2012.

描述

Bucladesine钙盐(DC2797钙盐)是PKA选择性且细胞可通透激动剂。

相关类别

信号通路 >> 蛋白酪氨酸激酶 >> PKA

信号通路 >> 干细胞及 Wnt 通路 >> PKA

研究领域 >> 其他

参考文献

[1]. Sharifzadeh, M., et al., Post-training intrahippocampal infusion of nicotine-bucladesine combination causes a synergistic enhancement effect on spatial memory retention in rats. Eur J Pharmacol, 2007. 562(3): p. 212-20.

[2]. Azami, K., et al., The quantitative evaluation of cholinergic markers in spatial memory improvement induced by nicotine-bucladesine combination in rats. Eur J Pharmacol, 2010. 636(1-3): p. 102-7.

[3]. Mafune, E., M. Takahashi, and N. Takasugi, Effect of vehicles on percutaneous absorption of bucladesine (dibutyryl cyclic AMP) in normal and damaged rat skin. Biol Pharm Bull, 1995. 18(11): p. 1539-43.

[4]. Rundfeldt, C., et al., The stable cyclic adenosine monophosphate analogue, dibutyryl cyclo-adenosine monophosphate (bucladesine), is active in a model of acute skin inflammation. Arch Dermatol Res, 2012.

分子式	C₃₆H₄₆CaN₁₀O₁₆P₂
分子量	976.8
精确质量	976.2194403
InChIKey	RCFZVVHQICKFQW-NGVPHMJWSA-L
SMILES	CCCC(=O)NC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@H]4[C@H](O3)COP(=O)(O4)[O-])OC(=O)CCC.CCCC(=O)NC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@H]4[C@H](O3)COP(=O)(O4)[O-])OC(=O)CCC.[Ca+2]
储存条件	2-8℃

Butanoic acid, (4aR,6R,7R,7aR)-tetrahydro-2-hydroxy-2-oxido-6-[6-[(1-oxobutyl)amino]-9H-purin-9-yl]-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-7-yl ester, calcium salt (2:1)

(4aR,6R,7R,7aR)-6-[6-(Butyrylamino)-9H-purin-9-yl]-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl butanoate - calcium (2:1)

Bucladesine (calcium salt)