4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide

更新时间：2025-09-28 11:29:15

4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide结构式	常用名	4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide	英文名	4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide
	CAS号	942296-25-5	分子量	345.13
	密度	N/A	沸点	N/A
	分子式	C₁₂H₁₂INO₃	熔点	N/A
	MSDS	美版	闪点	N/A

英文名	4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide
英文别名	更多

分子式	C₁₂H₁₂INO₃
分子量	345.13
InChIKey	IMJUHEKUNKCNGB-JTQLQIEISA-N
SMILES	O=C(Cc1ccc(I)cc1)NC1CCOC1=O
储存条件	−20°C

危险品运输编码	NONH for all modes of transport

Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-Acyl homoserine lactones.

ACS Chem. Biol. 7(10) , 1719-28, (2012)

Many bacterial pathogens use quorum sensing (QS) to control virulence. As a result, the development of methods to intercept QS has attracted significant interest as a potential anti-infective therapy....

Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action.

J. Am. Chem. Soc. 129(44) , 13613-25, (2007)

Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathog...

Small molecule disruption of quorum sensing cross-regulation in pseudomonas aeruginosa causes major and unexpected alterations to virulence phenotypes.

J. Am. Chem. Soc. 137(4) , 1510-9, (2015)

The opportunistic pathogen Pseudomonas aeruginosa uses three interwoven quorum-sensing (QS) circuits-Las, Rhl, and Pqs-to regulate the global expression of myriad virulence-associated genes. Intercept...

实验名称：Antagonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia ...
来源：ChEMBL
靶标：Transcriptional activator protein LasR
External Id：CHEMBL1827922

实验名称：Antagonist activity at Aliivibrio fischeri ES114 LuxR after 4 to 8 hrs by luminescenc...
来源：ChEMBL
靶标：Transcriptional activator protein LuxR
External Id：CHEMBL4404064

实验名称：Antagonist activity at Escherichia coli DH5alpha LasR receptor assessed as inhibition...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL1016858

实验名称：Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of ...
来源：ChEMBL
靶标：Transcriptional activator protein LuxR
External Id：CHEMBL1016859

实验名称：Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhi...
来源：ChEMBL
靶标：Transcriptional activator protein TraR
External Id：CHEMBL1016857

实验名称：Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL
来源：ChEMBL
靶标：Transcriptional activator protein LuxR
External Id：CHEMBL1827785

实验名称：Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM ...
来源：ChEMBL
靶标：Transcriptional activator protein TraR
External Id：CHEMBL1827786

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4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide

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