3-(Imidazo[1,2-a]pyrazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

• 常用名: 3-(Imidazo[1,2-a]pyrazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
• 英文名: 3-(Imidazo[1,2-a]pyrazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
• CAS号: 943319-55-9
• 分子量: 532.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₂₇F₃N₆O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-(Imidazo[1,2-a]pyrazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

物理化学性质

• 分子式: C₂₉H₂₇F₃N₆O
• 分子量: 532.6
• InChIKey: LUGNORFTBOIQFV-UHFFFAOYSA-N
• SMILES: Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2cnccn12

靶点实验

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实验名称：AUC (0 to 24 hrs) in CD rat at 30 mg/kg, po by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1176877

实验名称：Oral bioavailability in CD rat at 15 mg/kg by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1176876

实验名称：Half life in CD rat at 15 mg/kg, po by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1176875

实验名称：Tmax in CD rat at 15 mg/kg, po by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1176874

实验名称：Cmax in CD rat at 15 mg/kg, po by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1176873

实验名称：Dose normalized AUC (0 to 24 hrs) in CD rat at 15 mg/kg, po by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1176872

实验名称：Half life in CD rat at 5 mg/kg, iv by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1176871

实验名称：Volume of distribution in CD rat at 5 mg/kg, iv by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1176870

实验名称：Half life in CD rat at 30 mg/kg, po by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1176883

实验名称：Cmax in CD rat at 30 mg/kg, po by LC-MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1176880

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