6-[6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl]-quinoline

• 常用名: 6-[6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl]-quinoline
• 英文名: 6-[6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl]-quinoline
• CAS号: 943540-16-7
• 分子量: 341.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₅N₇
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 6-[6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl]-quinoline

物理化学性质

• 分子式: C₁₉H₁₅N₇
• 分子量: 341.4
• InChIKey: NSNLFHBIYLDZLA-UHFFFAOYSA-N
• SMILES: Cn1cc(-c2ccc3nnc(Cc4ccc5ncccc5c4)n3n2)cn1

靶点实验

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实验名称：In Vitro Assay from US Patent US9066954: "Fused heterocyclic derivatives and methods ... 来源：BindingDB 靶标：N/A External Id：BindingDB_6998_1

实验名称：Kinetic solubility of the compound at pH 6.5 来源：ChEMBL 靶标：N/A External Id：CHEMBL2433358

实验名称：Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 4... 来源：ChEMBL 靶标：Hepatocyte growth factor receptor External Id：CHEMBL3369646

实验名称：Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA 来源：ChEMBL 靶标：Hepatocyte growth factor receptor External Id：CHEMBL3369647

实验名称：Inhibition of N-terminal His-6-tagged human recombinant c-Met (974 to 1390) using Ac-... 来源：ChEMBL 靶标：Hepatocyte growth factor receptor External Id：CHEMBL2434668

实验名称：Inhibition of c-Met autophosphorylation in human A549 cells after 1 hr by ELISA 来源：ChEMBL 靶标：Hepatocyte growth factor receptor External Id：CHEMBL2433360

实验名称：Apparent intrinsic clearance in human liver microsomes at 1 uM after 30 mins by LC-MS... 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL2433359

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