2-Amino-5-[2-morpholin-4-yl-6-(quinolin-3-ylamino)-pyrimidin-4-yl]-isonicotinonitrile

• 常用名: 2-Amino-5-[2-morpholin-4-yl-6-(quinolin-3-ylamino)-pyrimidin-4-yl]-isonicotinonitrile
• 英文名: 2-Amino-5-[2-morpholin-4-yl-6-(quinolin-3-ylamino)-pyrimidin-4-yl]-isonicotinonitrile
• CAS号: 944396-02-5
• 分子量: 424.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₀N₈O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-Amino-5-[2-morpholin-4-yl-6-(quinolin-3-ylamino)-pyrimidin-4-yl]-isonicotinonitrile

物理化学性质

• 分子式: C₂₃H₂₀N₈O
• 分子量: 424.5
• InChIKey: HLWTXVAXGWFIGD-UHFFFAOYSA-N
• SMILES: N#Cc1cc(N)ncc1-c1cc(Nc2cnc3ccccc3c2)nc(N2CCOCC2)n1

靶点实验

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实验名称：Antiproliferative activity against human A2780 cells after 3 days by CellTiter-Glo as... 来源：ChEMBL 靶标：A2780 External Id：CHEMBL2020155

实验名称：Inhibition of PI3K-mediated AKT Ser473 phosphorylation in human A2780 cells after 1 h... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2020156

实验名称：Inhibition of PI3Kalpha using 1-alpha-phosphatidylinositol as substrate by ATP deplet... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL2020154

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