Sirtuin-1 inhibitor 1

• 常用名: Sirtuin-1 inhibitor 1
• 英文名: Sirtuin-1 inhibitor 1
• CAS号: 945114-10-3
• 分子量: 331.37
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₇N₃O₂
• 熔点: N/A
• 闪点: N/A

Sirtuin-1 inhibitor 1用途

Sirtuin-1 inhibitor 1 (Compound 8) 是去乙酰化酶-1 (Sirtuin-1) 的抑制剂。Sirtuin-1 inhibitor 1 在肥胖引起的糖尿病和衰老相关疾病的研究中有重要作用。

Sirtuin-1 inhibitor 1名称

• 英文名: Sirtuin-1 inhibitor 1

Sirtuin-1 inhibitor 1生物活性

• 描述: Sirtuin-1 inhibitor 1 (Compound 8) 是去乙酰化酶-1 (Sirtuin-1) 的抑制剂。Sirtuin-1 inhibitor 1 在肥胖引起的糖尿病和衰老相关疾病的研究中有重要作用。
• 相关类别:
  信号通路 >> 表观遗传学 >> 抗衰老酶
  信号通路 >> 细胞周期/DNA损伤 >> 抗衰老酶
  研究领域 >> 代谢疾病
• 靶点实验:

  SIRT1

• 参考文献:

  [1]. Anastasiia Gryniukova, et al. AI-Powered Virtual Screening of Large Compound Libraries Leads to the Discovery of Novel Inhibitors of Sirtuin-1. J Med Chem. 2023 Aug 10;66(15):10241-10251.

Sirtuin-1 inhibitor 1物理化学性质

• 分子式: C₂₀H₁₇N₃O₂
• 分子量: 331.37

Sirtuin-1 inhibitor 1靶点实验

查看更多实验

实验名称：Antiproliferative activity against human HT-29 cells assessed as reduction in cell gr... 来源：ChEMBL 靶标：HT-29 External Id：CHEMBL4772148

实验名称：Antiproliferative activity against human A549 cells assessed as reduction in cell gro... 来源：ChEMBL 靶标：A549 External Id：CHEMBL4772149

实验名称：Binding affinity to carbonic anhydrase (unknown origin) assessed as change in melting... 来源：ChEMBL 靶标：Carbonic anhydrase 3 External Id：CHEMBL5364134

实验名称：Inhibition of Sirtuin-1 (unknown origin) incubated for 30 mins by luminogenic SIRT-Gl... 来源：ChEMBL 靶标：NAD-dependent protein deacetylase sirtuin-1 External Id：CHEMBL5364135

实验名称：Binding affinity to human recombinant truncated Sirtuin-1 expressed in Escherichia co... 来源：ChEMBL 靶标：NAD-dependent protein deacetylase sirtuin-1 External Id：CHEMBL5364132

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