8-chloro-4-hydroxy-N-(2-methoxyphenyl)quinoline-3-carboxamide

• 常用名: 8-chloro-4-hydroxy-N-(2-methoxyphenyl)quinoline-3-carboxamide
• 英文名: 8-chloro-4-hydroxy-N-(2-methoxyphenyl)quinoline-3-carboxamide
• CAS号: 951970-17-5
• 分子量: 328.7
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₃ClN₂O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 8-chloro-4-hydroxy-N-(2-methoxyphenyl)quinoline-3-carboxamide

物理化学性质

• 分子式: C₁₇H₁₃ClN₂O₃
• 分子量: 328.7
• InChIKey: KBXVKELVFMLQNL-UHFFFAOYSA-N
• SMILES: COc1ccccc1NC(=O)c1c[nH]c2c(Cl)cccc2c1=O

靶点实验

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实验名称：Positive allosteric modulation of GluN1/GluN2A receptor (unknown origin) stably expre... 来源：ChEMBL 靶标：Glutamate receptor ionotropic, NMDA 2A External Id：CHEMBL5255934

实验名称：Positive allosteric modulation of GluN1/GluN2B receptor (unknown origin) stably expre... 来源：ChEMBL 靶标：Glutamate receptor ionotropic, NMDA 2B External Id：CHEMBL5255943

实验名称：Cytotoxicity in rat PC-12 cells assessed as reduction in cell viability at 10 uM incu... 来源：ChEMBL 靶标：PC-12 External Id：CHEMBL5255940

实验名称：Neuroprotective activity against glutamate-induced neurotoxicity in rat PC-12 cells a... 来源：ChEMBL 靶标：PC-12 External Id：CHEMBL5255939

实验名称：Solubility of the compound in water by UV spectophotometry analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5255941

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify activators of... 来源：The Scripps Research Institute Molecular Screening Center 靶标：N/A External Id：FBW7_ACT_ALPHA_1536_1X%ACT PRUN

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Neuroprotective activity in middle cerebral artery occlusion-induced C57BL/6 mouse mo... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5255935

实验名称：Neuroprotective activity against glutamate-induced neurotoxicity in rat PC-12 cells a... 来源：ChEMBL 靶标：PC-12 External Id：CHEMBL5255938

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