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6-溴-1-(喹啉-6-甲基)-1H-1,2,3-噻唑并[4,5-b]吡嗪

更新时间:2024-01-02 17:18:50

6-溴-1-(喹啉-6-甲基)-1H-1,2,3-噻唑并[4,5-b]吡嗪结构式
6-溴-1-(喹啉-6-甲基)-1H-1,2,3-噻唑并[4,5-b]吡嗪结构式
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常用名 6-溴-1-(喹啉-6-甲基)-1H-1,2,3-噻唑并[4,5-b]吡嗪 英文名 6-[(5-bromotriazolo[4,5-b]pyrazin-3-yl)methyl]quinoline
CAS号 956907-14-5 分子量 341.16500
密度 N/A 沸点 N/A
分子式 C14H9BrN6 熔点 N/A
MSDS N/A 闪点 N/A

 名称

中文名 6-溴-1-(喹啉-6-甲基)-1H-1,2,3-噻唑并[4,5-b]吡嗪
英文名 6-[(5-bromotriazolo[4,5-b]pyrazin-3-yl)methyl]quinoline

 物理化学性质

分子式 C14H9BrN6
分子量 341.16500
精确质量 340.00700
PSA 69.38000
LogP 2.58030

 合成线路

~72%

6-溴-1-(喹啉-6-甲基)-1H-1,2,3-噻唑并[4,5-b]吡嗪结构式

6-溴-1-(喹啉-6-甲基)...

956907-14-5

文献:Cui, J. Jean; McTigue, Michele; Nambu, Mitchell; Tran-Dube, Michelle; Pairish, Mason; Shen, Hong; Jia, Lei; Cheng, Hengmiao; Hoffman, Jacqui; Le, Phuong; Jalaie, Mehran; Goetz, Gilles H.; Ryan, Kevin; Grodsky, Neil; Deng, Ya-Li; Parker, Max; Timofeevski, Sergei; Murray, Brion W.; Yamazaki, Shinji; Aguirre, Shirley; Li, Qiuhua; Zou, Helen; Christensen, James Journal of Medicinal Chemistry, 2012 , vol. 55, # 18 p. 8091 - 8109,19 Title/Abstract Full Text Show Details Cui, J. Jean; McTigue, Michele; Nambu, Mitchell; Tran-Dube, Michelle; Pairish, Mason; Shen, Hong; Jia, Lei; Cheng, Hengmiao; Hoffman, Jacqui; Le, Phuong; Jalaie, Mehran; Goetz, Gilles H.; Ryan, Kevin; Grodsky, Neil; Deng, Ya-Li; Parker, Max; Timofeevski, Sergei; Murray, Brion W.; Yamazaki, Shinji; Aguirre, Shirley; Li, Qiuhua; Zou, Helen; Christensen, James Journal of Medicinal Chemistry, 2012 , vol. 55, # 18 p. 8091 - 8109

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6-溴-1-(喹啉-6-甲基)-1H-1,2,3-噻唑并[4,5-b]吡嗪结构式

6-溴-1-(喹啉-6-甲基)...

956907-14-5

文献:NOVARTIS AG; FU, Xingnian; HE, Feng; LI, Yue; LIU, Lei; MI, Yuan; XU, Yao-chang; XUN, Guoliang; YU, Zhengtian; ZHANG, Ji Yue (Jeff); DAI, Miao Patent: WO2011/18454 A1, 2011 ; WO 2011/018454 A1 Title/Abstract Full Text Show Details NOVARTIS AG; DAI, Miao; FU, Xingnian; HE, Feng; JIANG, Lei; LI, Yue; LIANG, Fang; LIU, Lei; MI, Yuan; XU, Yao-chang; XUN, Guoliang; YAN, Xiaoxia; YU, Zhengtian; ZHANG, Ji, Yue Patent: WO2011/20861 A1, 2011 ;

~%

6-溴-1-(喹啉-6-甲基)-1H-1,2,3-噻唑并[4,5-b]吡嗪结构式

6-溴-1-(喹啉-6-甲基)...

956907-14-5

文献:NOVARTIS AG; FU, Xingnian; HE, Feng; LI, Yue; LIU, Lei; MI, Yuan; XU, Yao-chang; XUN, Guoliang; YU, Zhengtian; ZHANG, Ji Yue (Jeff); DAI, Miao Patent: WO2011/18454 A1, 2011 ; WO 2011/018454 A1

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6-溴-1-(喹啉-6-甲基)-1H-1,2,3-噻唑并[4,5-b]吡嗪结构式

6-溴-1-(喹啉-6-甲基)...

956907-14-5

文献:NOVARTIS AG; FU, Xingnian; HE, Feng; LI, Yue; LIU, Lei; MI, Yuan; XU, Yao-chang; XUN, Guoliang; YU, Zhengtian; ZHANG, Ji Yue (Jeff); DAI, Miao Patent: WO2011/18454 A1, 2011 ; WO 2011/018454 A1

~%

6-溴-1-(喹啉-6-甲基)-1H-1,2,3-噻唑并[4,5-b]吡嗪结构式

6-溴-1-(喹啉-6-甲基)...

956907-14-5

文献:NOVARTIS AG; FU, Xingnian; HE, Feng; LI, Yue; LIU, Lei; MI, Yuan; XU, Yao-chang; XUN, Guoliang; YU, Zhengtian; ZHANG, Ji Yue (Jeff); DAI, Miao Patent: WO2011/18454 A1, 2011 ; WO 2011/018454 A1 Title/Abstract Full Text Show Details NOVARTIS AG; DAI, Miao; FU, Xingnian; HE, Feng; JIANG, Lei; LI, Yue; LIANG, Fang; LIU, Lei; MI, Yuan; XU, Yao-chang; XUN, Guoliang; YAN, Xiaoxia; YU, Zhengtian; ZHANG, Ji, Yue Patent: WO2011/20861 A1, 2011 ;
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