Psb-6426

• 常用名: Psb-6426
• 英文名: Psb-6426
• CAS号: 958459-33-1
• 分子量: 540.46
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₂₉N₄O₁₀P
• 熔点: N/A
• 闪点: N/A

Psb-6426用途

PSB-6426是第一个有效和选择性的人核苷三磷酸二磷酸脱氢酶-2抑制剂。

Psb-6426名称

• 英文名: PSB-6426

Psb-6426生物活性

• 描述: PSB-6426是第一个有效和选择性的人核苷三磷酸二磷酸脱氢酶-2抑制剂。
• 参考文献: 1. Hayashi M, Inagaki A, Novak I, Matsuda H. The adenosine A2B receptor is involved in anion secretion in human pancreatic duct Capan-1 epithelial cells. Pflugers Arch. 2016 Jul;468(7):1171-81. doi: 10.1007/s00424-016-1806-9. Epub 2016 Mar 11. PubMed PMID: 26965147; PubMed Central PMCID: PMC4943985.

Psb-6426物理化学性质

• 分子式: C₂₂H₂₉N₄O₁₀P
• 分子量: 540.46
• InChIKey: AEVBPXDFDKBGLT-YOUFYPILSA-N
• SMILES: CCOP(=O)(Cc1ccc(NC(=O)CNC(=O)C2OC(n3ccc(=O)[nH]c3=O)C(O)C2O)cc1)OCC

Psb-6426靶点实验

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实验名称：Antagonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed a... 来源：ChEMBL 靶标：P2Y purinoceptor 2 External Id：CHEMBL968886

实验名称：Antagonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed a... 来源：ChEMBL 靶标：P2Y purinoceptor 2 External Id：CHEMBL968894

实验名称：Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as ... 来源：ChEMBL 靶标：P2Y purinoceptor 6 External Id：CHEMBL968888

实验名称：Antagonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed a... 来源：ChEMBL 靶标：P2Y purinoceptor 4 External Id：CHEMBL968887

实验名称：Metabolic stability in rat liver microsomes after 24 hrs by LC-MS analysis 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL968899

实验名称：Inhibition of human NTPDase 1 expressed in COS7 cells at 1mM 来源：ChEMBL 靶标：Ectonucleoside triphosphate diphosphohydrolase 1 External Id：CHEMBL979119

实验名称：Inhibition of human NTPDase 2 expressed in HEK293 cells 来源：ChEMBL 靶标：Ectonucleoside triphosphate diphosphohydrolase 2 External Id：CHEMBL979122

实验名称：Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as ... 来源：ChEMBL 靶标：P2Y purinoceptor 6 External Id：CHEMBL968895

实验名称：Stability in simulated artificial gastric juice after 24 hrs by LC-MS analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL968898

实验名称：Antagonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed a... 来源：ChEMBL 靶标：P2Y purinoceptor 4 External Id：CHEMBL979118

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