3-(5-(4-Cyclobutyl-1,4-diazepane-1-carbonyl)pyridin-2-yloxy)benzonitrile

• 常用名: 3-(5-(4-Cyclobutyl-1,4-diazepane-1-carbonyl)pyridin-2-yloxy)benzonitrile
• 英文名: 3-(5-(4-Cyclobutyl-1,4-diazepane-1-carbonyl)pyridin-2-yloxy)benzonitrile
• CAS号: 959740-40-0
• 分子量: 376.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₂₄N₄O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-(5-(4-Cyclobutyl-1,4-diazepane-1-carbonyl)pyridin-2-yloxy)benzonitrile

物理化学性质

• 分子式: C₂₂H₂₄N₄O₂
• 分子量: 376.5
• InChIKey: WWZNPNMHGHEVNB-UHFFFAOYSA-N
• SMILES: N#Cc1cccc(Oc2ccc(C(=O)N3CCCN(C4CCC4)CC3)cn2)c1

靶点实验

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实验名称：Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells ass... 来源：ChEMBL 靶标：Histamine H3 receptor External Id：CHEMBL1175769

实验名称：Antagonist activity at human histamine H3 receptor expressed in human SK-N-MC cells a... 来源：ChEMBL 靶标：Histamine H3 receptor External Id：CHEMBL1175768

实验名称：Displacement of [125I]-iodoproxyfan from human recombinant histamine H3 receptor expr... 来源：ChEMBL 靶标：Histamine H3 receptor External Id：CHEMBL1175767

实验名称：Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv and 10 mg... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1175777

实验名称：Clearance in Sprague-Dawley rat at 1 mg/kg, iv and 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1175776

实验名称：Binding affinity to histamine H3 receptor in rat brain 来源：ChEMBL 靶标：Histamine H3 receptor External Id：CHEMBL1175775

实验名称：Plasma concentration in Wistar rat at 10 mg/kg, po after 1 hr 来源：ChEMBL 靶标：Plasma External Id：CHEMBL1175774

实验名称：Drug level in Wistar rat brain at 10 mg/kg, po after 1 hr 来源：ChEMBL 靶标：Brain External Id：CHEMBL1175773

实验名称：Ex vivo receptor occupancy of histamine H3 receptor in Wistar rat brain at 10 mg/kg, ... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1175772

实验名称：Metabolic stability in human liver microsomes assessed as compound remaining after 30... 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1175771

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