1-(2-((2,4-二甲基苯基)硫基)苯基)哌嗪盐酸盐

• 常用名: 1-(2-((2,4-二甲基苯基)硫基)苯基)哌嗪盐酸盐
• 英文名: 1-[2-(2,4-DiMethylphenylsulfanyl)phenyl]piperazine Hydrochloride
• CAS号: 960203-28-5
• 分子量: 334.90700
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₂₃ClN₂S
• 熔点: N/A
• 闪点: N/A

名称

• 中文名: 沃替西汀盐酸盐
• 英文名: Vortioxetine hydrochloride

物理化学性质

• 分子式: C₁₈H₂₃ClN₂S
• 分子量: 334.90700
• 精确质量: 334.12700
• PSA: 40.57000
• LogP: 5.06000
• 储存条件: 室温

靶点实验

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实验名称：Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells b... 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 3A External Id：CHEMBL2215843

实验名称：Antidepression activity in sc dosed Harlan rat assessed as increase in extracellular ... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2215844

实验名称：Inhibition of SERT-mediated [3H]5HT uptake in rat synaptosomes by scintillation count... 来源：ChEMBL 靶标：Sodium-dependent serotonin transporter External Id：CHEMBL2215841

实验名称：Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells ... 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A External Id：CHEMBL2215842

实验名称：Selectivity ratio of IC50 for DAT to IC50 for SERT in rat synaptosomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL2215847

实验名称：Selectivity ratio of IC50 for NET to IC50 for SERT in rat synaptosomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL2215835

实验名称：Inhibition of NET-mediated [3H]NE in rat synaptosomes by scintillation counting 来源：ChEMBL 靶标：N/A External Id：CHEMBL2215836

实验名称：Inhibition of DAT-mediated [3H]DA in rat synaptosomes by scintillation counting 来源：ChEMBL 靶标：Sodium-dependent dopamine transporter External Id：CHEMBL2215837

实验名称：Antidepression activity in Harlan rat assessed as increase in extracellular 5HT level... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2215346

实验名称：Antidepression activity in Harlan rat assessed as increase in extracellular 5HT level... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2215344

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英文别名

• vortioxetine hydrochloride
• 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine hydrochloride
• 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine hydrochloride
• 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine hydrochloride
• 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine hydrochloride
• 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine hydrochloride