Clentiazem

• 常用名: Clentiazem
• 英文名: Clentiazem
• CAS号: 96125-53-0
• 分子量: 448.96300
• 密度: 1.32g/cm3
• 沸点: 626.4ºC at 760mmHg
• 分子式: C₂₂H₂₅ClN₂O₄S
• 熔点: N/A
• 闪点: 332.7ºC

Clentiazem名称

• 英文名: [(2S,3S)-8-chloro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate

Clentiazem物理化学性质

• 密度: 1.32g/cm3
• 沸点: 626.4ºC at 760mmHg
• 分子式: C₂₂H₂₅ClN₂O₄S
• 分子量: 448.96300
• 闪点: 332.7ºC
• 精确质量: 448.12200
• PSA: 84.38000
• LogP: 4.08690
• InChIKey: GYKFWCDBQAFCLJ-RTWAWAEBSA-N
• SMILES: COc1ccc(C2Sc3cc(Cl)ccc3N(CCN(C)C)C(=O)C2OC(C)=O)cc1

Clentiazem靶点实验

查看更多实验

实验名称：In vivo evaluation for the percentage decrease in blood pressure at 135 umol/kg admin... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL778335

实验名称：In vivo evaluation for the percentage decrease in blood pressure at 135 umol/kg admin... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL774254

实验名称：In vivo evaluation for the percentage decrease in blood pressure at 135 umol/kg admin... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL774395

实验名称：In vitro evaluation for the vasorelaxant effects in circumferential strips of potassi... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL771605

实验名称：In vitro evaluation for the vasorelaxant effects in circumferential strips of potassi... 来源：ChEMBL 靶标：Oryctolagus cuniculus External Id：CHEMBL771604

实验名称：Choleostatic liver toxicity, either proven histopathologically or where the ratio of ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137727

实验名称：Severe hepatitis, defined as possibly life-threatening liver failure or through clini... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137728

实验名称：Chronic liver disease either proven histopathologically, or through a chonic elevatio... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137729

实验名称：Cirrhosis, proven histopathologically. Value is number of references indexed. [column... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137730

实验名称：Granulomatous liver disease, proven histopathologically. Value is number of reference... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3137731

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Clentiazem英文别名

• Clentiazemum [INN-Latin]
• 1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-8-chloro-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-,(2S,3S)
• 8-chlorodiltiazem
• Clentiazem [INN]
• 1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-8-chloro-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-,(25-cis)
• Clentiazemum
• C22H25ClN2O4S
• (+/-)-Clentiazem
• (+)-(2S,3S)-cis-3-acetoxy-8-chloro-5-<2-(dimethylamino)ethyl>2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
• (+)-cis-2-(4-Methoxyphenyl)-3-acetoxy-5-(2-(N,N-dimethylamino)ethyl)-8-chloro-2,3-dihydro-1,5-benzothiazepin-4(5H)-one