Journal of medicinal chemistry

Chemotherapeutic nitroheterocycles. Nitropyrrole-2-carboxaldehyde derivatives

WT Colwell, JH Lange, DW Henry

Index: Colwell,W.T. et al. Journal of Medicinal Chemistry, 1968 , vol. 11, # 2 p. 282 - 285

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Citation Number: 5

Abstract

... C, H, S C, H, N C, H, N C, H, s C, H, S C, H, S ' J HJ C, H, Ii C, H, N C, H, ri C, H, K C, H, N C, H, N 40 mdke 0.2 ... F. Hoffman, FF Giarrusso, H. Schwaillin, and G. E. Artli, J . Ore. Chem., 27, 3822 (1962). 1,R=OH 2, R=CH(B-OH)CHB 4,3p, R = OH ... SCHEME 1 NaBH, 3 RO 7,R=Ac;R'=Br 8, R= H; R = H 9,20a 10,20f9 0 11 nitro compound, and (b) hydrolysis of the oxinie to the parent kctoric, arid subsequent reduction to the corrc- sponding alcohol by the borohydride. ...