Structure− activity relationships among random nylon-3 copolymers that mimic antibacterial host-defense peptides

…, B Weisblum, SS Stahl, SH Gellman

Index: Lee, Myung-Ryul; Stahl, Shannon S.; Gellman, Samuel Organic Letters, 2008 , vol. 10, # 22 p. 5317 - 5319

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Citation Number: 108

Abstract

Host-defense peptides are natural antibiotics produced by multicellular organisms to ward off bacterial infection. Since the discovery of these molecules in the 1980s, a great deal of effort has been devoted to elucidating their mechanisms of action and to developing