Journal of the American Chemical Society

Claisen condensation of methyl esters

EE Royals

Index: Royals Journal of the American Chemical Society, 1948 , vol. 70, p. 489

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Citation Number: 15

Abstract

Investigations of the acetoacetic ester condensation'have been largely confined to the study of ethyl esters; particularly, relatively few methyl ester condensations have been reported in the literature. The present commercial availa, bility of sodium methoxide, and observations* that sodium methoxide is a condensation catalyst considerably less sensitive to adverse experimental conditions than sodium ethoxide make furth. er investigation of methyl ester ...