A chromium-free synthesis of enantiopure 5-oxoborneol

S Tartaggia, P Padovan, G Borsato, O De Lucchi…

Index: Tartaggia, Stefano; Padovan, Pierluigi; Borsato, Giuseppe; De Lucchi, Ottorino; Fabris, Fabrizio Tetrahedron Letters, 2011 , vol. 52, # 34 p. 4478 - 4480

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Citation Number: 3

Abstract

Enantiopure (−)-5-oxoborneol was obtained in 35% overall yield in two steps, starting from readily available (−)-bornyl acetate and using oxone® as a safe and inexpensive oxidant. The reported procedure avoids the use of large excess of noxious chromium (VI), which was required by the so far reported syntheses.