Tetrahedron

Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation

SJ Pridmore, PA Slatford, JE Taylor, MK Whittlesey…

Index: Pridmore, Simon J.; Slatford, Paul A.; Taylor, James E.; Whittlesey, Michael K.; Williams, Jonathan M.J. Tetrahedron, 2009 , vol. 65, # 44 p. 8981 - 8986

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Citation Number: 27

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh 3 ) 3 (CO)H 2 /xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions. ... Synthesis of heterocycles from 1,4- ...