Tetrahedron Letters

The cation exchange resin-promoted coupling of alkynes with aldehydes: one-pot synthesis of α, β-unsaturated ketones

JS Yadav, BVS Reddy, P Vishnumurthy

Index: Yadav; Subba Reddy; Vishnumurthy Tetrahedron Letters, 2008 , vol. 49, # 29-30 p. 4498 - 4500

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Citation Number: 17

Abstract

Alkynes undergo smooth coupling with aldehydes in the presence of Amberlyst-15® at room temperature to produce the corresponding α, β-unsaturated ketones in high yields with E- geometry. The use of an inexpensive, readily available, and recyclable cation exchange resin makes this method quite simple and convenient.