Oxidation of primary amines to oximes with molecular oxygen using 1, 1-diphenyl-2-picrylhydrazyl and WO3/Al2O3 as catalysts

…, T Watanabe, SI Murahashi

Index: Suzuki, Ken; Watanabe, Tomonari; Murahashi, Shun-Ichi Journal of Organic Chemistry, 2013 , vol. 78, # 6 p. 2301 - 2310

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Citation Number: 18

Abstract

The oxidative transformation of primary amines to their corresponding oximes proceeds with high efficiency under molecular oxygen diluted with molecular nitrogen (O2/N2= 7/93 v/v, 5 MPa) in the presence of the catalysts 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and tungusten oxide/alumina (WO3/Al2O3). The method is environmentally benign, because the reaction requires only molecular oxygen as the terminal oxidant and gives water as a side product. ...