Tetrahedron Letters

A convenient one-pot procedure for synthesis of thiol esters using magnesium ion as a catalyst

S Ohta, M Okamoto

Index: Ohta, Shunsaku; Okamoto, Masao Tetrahedron Letters, 1981 , vol. 22, # 34 p. 3245 - 3246

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Citation Number: 18

Abstract

Abstract Various thiol esters (R 1 COSR 2) were prepared in high yields by treatment of 1- acylimidazole with thiols in the presence of a catalytic amount of Mg (OEt) 2. Malonic half- thiol esters [R 1 OCOCH (R 3) COSR 2] were also prepared in good yields by treating magnesium monoalkyl malonate [R 1 OCOCH (R 3) COOMg12] with carbonyl-1, 1′- diimidazole followed by addition of thiols.