The Journal of Organic Chemistry

Effect of catalyst on the fluorination of methyl-substituted benzenes with xenon difluoride

S Stavber, M Zupan

Index: Stavber, Stojan; Zupan, Marko Journal of Organic Chemistry, 1983 , vol. 48, # 13 p. 2223 - 2226

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Citation Number: 22

Abstract

The course of acid-catalyzed liquid-phase fluorination of methyl-substituted benzene derivatives with xenon difluoride depends strongly on the structure and concentration of the substrate, ita molar ratio to xenon dffluoride, and the catalyst. HF-catalyzed fluorination of 1, 2, 4, 5-tetramethylbnzene (1) with an equimolar amount of xenon difluoride gave a small amount of l&difluoro product 2, while reaction with 2 equiv of xenon difluoride, besides ...