e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Journal of the American Chemical Society

Palladium-Catalyzed Cleavage Reaction of Carbon− Carbon Triple Bond with Molecular Oxygen Promoted by Lewis Acid

A Wang, H Jiang

Index: Wang, Azhong; Jiang, Huanfeng Journal of the American Chemical Society, 2008 , vol. 130, # 15 p. 5030 - 5031

Full Text: HTML

Citation Number: 92

Abstract

Transition-metal-catalyzed cleavage reactions of carbon−carbon bonds have been recognized as powerful tools in organic transformations.(1) Various unique and useful catalytic processes involving C−C single and double bonds cleavage have recently been developed.(2) What has remained unexplored is the cleavage of C−C triple bond, which is one of the most challenging subjects in modern synthetic organic chemistry.(3) Most studies on alkyne cleavage have ...

Methanol Structure

1-Octynylbenzene Structure

1-Octynylbenzene

~0%

Propyl heptanoate Structure

Propyl heptanoate

Ethyl benzoate Structure

1-Propanol Structure

hexadeca-7,9-diyne Structure

hexadeca-7,9-diyne

~74%

Propyl heptanoate Structure

Propyl heptanoate

1-Propanol Structure

Oct-1-yne Structure

~75%

Propyl heptanoate Structure

Propyl heptanoate

Methanol Structure

Anisole, p-(phenylethynyl)- Structure

Anisole, p-(phe...

~86%

Methyl benzoate Structure

Methyl benzoate

Methyl anisate Structure

Methanol Structure

1-Nitro-4-phenylethynyl-benzene Structure

1-Nitro-4-pheny...

~89%

Methyl benzoate Structure

Methyl benzoate

Methyl 4-nitrobenzoate Structure

Methyl 4-nitrob...

Methanol Structure

DI-P-TOLYLACETYLENE Structure

DI-P-TOLYLACETYLENE

~91%

methyl p-toluate Structure

methyl p-toluate

Methanol Structure

1-METHYL-4-PHENYLETHYNYL-BENZENE Structure

1-METHYL-4-PHEN...

~0%

Methyl benzoate Structure

Methyl benzoate

methyl p-toluate Structure

methyl p-toluate

1-Propanol Structure

Diphenylacetylene Structure

Diphenylacetylene

~80%

Propyl benzoate Structure

Propyl benzoate

Methanol Structure

1-Bromo-4-(phenylethynyl)benzene Structure

1-Bromo-4-(phen...

~83%

Methyl benzoate Structure

Methyl benzoate

Methyl 4-bromobenzoate Structure

Methyl 4-bromob...

Ethanol Structure

Diphenylacetylene Structure

Diphenylacetylene

~86%

Ethyl benzoate Structure

Methanol Structure

1-Octynylbenzene Structure

1-Octynylbenzene

~85%

Propyl heptanoate Structure

Propyl heptanoate

Ethyl benzoate Structure