Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor α agonists

Y Yamazaki, K Abe, T Toma, M Nishikawa…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 16 p. 4689 - 4693

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Citation Number: 26

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... These observations suggest the possibility of identifying chemical structures capable of exhibiting high affinity for PPARα by introducing several hydrocarbon chains in our drug design. ...