Enoate reductase-mediated preparation of methyl (S)-2-bromobutanoate, a useful key intermediate for the synthesis of chiral active pharmaceutical ingredients

E Brenna, FG Gatti, A Manfredi, D Monti…

Index: Olah, George A.; Shih, Joseph; Prakash, G. K. Surya Helvetica Chimica Acta, 1983 , vol. 66, # 4 p. 1028 - 1030

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Citation Number: 38

Abstract

... Volume: Page: ... Istituto di Chimica del Riconoscimento ... processes and can be carried out by enzyme catalysis with the use of enoate reductases.(3) The corresponding reaction performed by hydrogenation in the presence of chiral metal complexes(4) has been ...