Tetrahedron

Flavonoid metabolism: the synthesis of phenolic glucuronides and sulfates as candidate metabolites for bioactivity studies of dietary flavonoids

…, NP Botting, AMZ Slawin, CD Kay, D O'Hagan

Index: Zhang, Qingzhi; Raheem, K. Saki; Botting, Nigel P.; Slawin, Alexandra M.Z.; Kay, Colin D.; O'Hagan, David Tetrahedron, 2012 , vol. 68, # 22 p. 4194 - 4201

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Citation Number: 18

Abstract

Epidemiological studies indicate that flavonoid intake is inversely associated with the risk of coronary heart disease, yet the mechanisms responsible for their bioactivity are still a matter of debate. Based on the rapid and extensive metabolism of most flavonoids, their health effects most likely result from the biological activity of their metabolites. However, a lack of commercially available compounds/standards has prevented the study of metabolite ...