Tetrahedron: Asymmetry

Towards the chemoenzymatic synthesis of lipid A

T Sugai, H Ritzén, CH Wong

Index: Sugai, Takeshi; Ritzen, Helena; Wong, Chi-Huey Tetrahedron: Asymmetry, 1993 , vol. 4, # 5 p. 1051 - 1058

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Citation Number: 29

Abstract

Abstract New procedures have been developed for the synthesis of the two important components of lipid A; one is the lipase-catalyzed resolution of 3-hydroxyteradecanoic acid in tetrahydrofuran using vinyl acetate and the other is the synthesis of the disaccharide moiety using glycosylphosphite as the glycosylating reagenL