Journal of the American Chemical Society

Quinolinequinones. II. N-Substituted 6-Amino-5, 8-quinolinequinones1

YT Pratt, NL Drake

Index: Pratt; Drake Journal of the American Chemical Society, 1955 , vol. 77, p. 37,39

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Citation Number: 13

Abstract

Taylor and Greenberg3 have shown that certain 6-hydroxyquinolines with diethylaminoalkylamino side chains at the 8-position are effective amebicides against E. histolytica in guinea pigs. The hydroquinone of 8-isopropylaminoamylamino-5, 6-quinoline- quinone, which is rapidly converted to the quinone by air, 2 is slightly active despite the fact that the quinone is not stable and is probably rapidly destroyed in vivo. It was therefore of ...