Journal of Heterocyclic Chemistry

Novel and Convenient Synthesis of Benzofurans from Dihydrocoumarins

S Shachan??Tov, AA Frimer

Index: Shachan-Tov, Sharona; Frimer, Aryeh A. Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 4 p. 905 - 908

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Citation Number: 2

Abstract

Abstract 7-Hydroxy-3, 4-dihydrocoumarin-4-carboxylic acid (7), conveniently prepared from m-resorcinol and maleic anhydride, was surprisingly transformed by acid anhydride and pyridine into the corresponding ketone, 4-alkanoyl analog 11. The latter reacted in turn with acidic alcohol yielding benzofuran-3-yl-acetic ester 16.