Application of microreactor technology in process development

X Zhang, S Stefanick, FJ Villani

Index: Zhang, Xini; Stefanick, Stephen; Villani, Frank J. Organic Process Research and Development, 2004 , vol. 8, # 3 p. 455 - 460

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Citation Number: 159

Abstract

The microreactor technology is an efficient tool for kilogram-scale syntheses in continuous mode and is particularly effective for hazardous reactions that do not allow scale-up in conventional reactors. Applications to several classes of reactions including highly exothermic reactions, high-temperature reactions, reactions with unstable intermediates, and reactions involving hazardous reagents are described herein.