Rhodium-Catalyzed Oxidative ortho-Acylation of Benzamides with Aldehydes: Direct Functionalization of the sp2 C–H Bond

…, E Park, A Kim, Y Lee, KW Chi, JH Kwak, YH Jung…

Index: Park, Jihye; Park, Eonjeong; Kim, Aejin; Lee, Youngil; Chi, Ki-Whan; Kwak, Jong Hwan; Jung, Young Hoon; Kim, In Su Organic Letters, 2011 , vol. 13, # 16 p. 4390 - 4393

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Citation Number: 109

Abstract

A rhodium-catalyzed oxidative acylation of benzamides with aryl aldehydes via direct sp2 C– H bond cleavage is described. In the presence of [Cp* RhCl2] 2, AgSbF6, and silver carbonate as an oxidant, N, N-diethyl benzamides can be effectively carbonylated to yield ortho-acyl benzamides.