Metal??Free Oxidative Coupling Reactions via σ??Iodonium Intermediates: The Efficient Synthesis of Bithiophenes Using Hypervalent Iodine Reagents

K Morimoto, T Nakae, N Yamaoka…

Index: Morimoto, Koji; Nakae, Tomofumi; Yamaoka, Nobutaka; Dohi, Toshifumi; Kita, Yasuyuki European Journal of Organic Chemistry, 2011 , # 31 p. 6326 - 6334

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Citation Number: 20

Abstract

Abstract The direct oxidative biaryl coupling reaction is an attractive tool for environmentally benign green chemistry. A novel direct method for the synthesis of bithiophene using a hypervalent iodine reagent has been developed. The reaction mechanism has also been investigated, casting light on the reaction intermediate and revealing the reactivity with iodonium salts.