Synthesis of. alpha.-ketols mediated by divalent samarium compounds

J Collin, JL Namy, F Dallemer…

Index: Collin, Jacqueline; Namy, Jean-Louis; Dallemer, Frederic; Kagan, Henri B. Journal of Organic Chemistry, 1991 , vol. 56, # 9 p. 3118 - 3122

Full Text: HTML

Citation Number: 70

Abstract

Coupling reactions of acid chlorides are mediated by SmI, and SmCp,, leading to a-ketols 3. Condensation reactions of acid chlorides on aldehydes similarly product a-ketols 5; with ketones, best results are obtained with use of SmIP Reactivities of SmIz and SmCp, are compared and mechanisms of the reactions discussed. Formation of an acylsamarium species is shown.