Leucodaunomycins, new intermediates in the redox chemistry of daunomycin

DM Bird, G Gaudiano, TH Koch

Index: Journal of the American Chemical Society, , vol. 113, # 1 p. 308 - 315

Full Text: HTML

Citation Number: 16

Abstract

... and hydroxyl radical.I4-I6 The chemistry of anthracycline quinone methides has been studied 'US. ... 1347. 0002-7863/9 1 / 15 13-308$02.50/0 0 199 1 American Chemical Society ... and Fisher30 on the structure of leuco-7-deoxydaunomycinone (4), and the chemical reactivity (vide ...

 Related Synthetic Route
(8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy)-6a,7,8,9,10,10a-hexahydro-5,8,12-trihydroxy-1-methoxy-6,11-naphthacenedione Structure

118868-84-1

(8S-cis)-8-acet...

~%

Daunomycinone Structure

21794-55-8

Daunomycinone

7-deoxydaunomycinone Structure

32384-98-8

7-deoxydaunomycinone

(8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy)-6a,7,8,9,10,10a-hexahydro-5,8,12-trihydroxy-1-methoxy-6,11-naphthacenedione Structure

118868-84-1

(8S-cis)-8-acet...

~%

Daunorubicin Structure

20830-81-3

Daunorubicin

Daunomycinone Structure

21794-55-8

Daunomycinone

9-acetyl-7,8,9,10-tetrahydro-6,9,11-trihydroxy-4-methoxy-7-oxonaphthacene-5,12-quinone Structure

32469-41-3

9-acetyl-7,8,9,...

Detail
(8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy)-6a,7,8,9,10,10a-hexahydro-5,8,12-trihydroxy-1-methoxy-6,11-naphthacenedione Structure

118868-84-1

(8S-cis)-8-acet...

~%

Daunorubicin Structure

20830-81-3

Daunorubicin

Daunomycinone Structure

21794-55-8

Daunomycinone

9-acetyl-7,8,9,10-tetrahydro-6,9,11-trihydroxy-4-methoxy-7-oxonaphthacene-5,12-quinone Structure

32469-41-3

9-acetyl-7,8,9,...

Detail

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