Tetrahedron letters

Reduction of propargylic sulfones to (Z)-allylic sulfones using zinc and ammonium chloride

HM Sheldrake, TW Wallace

Index: Sheldrake, Helen M.; Wallace, Timothy W. Tetrahedron Letters, 2007 , vol. 48, # 25 p. 4407 - 4411

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Citation Number: 19

Abstract

Propargylic sulfones can be cis-hydrogenated using commercial zinc powder and ammonium chloride in THF–water at room temperature, the major products being the corresponding (Z)-allylic sulfones. Other reducible groups (alkene, benzyloxy) are not affected. Allenylsulfones are implicated in one of the possible reaction pathways.