Identification of cinnamic acid derivatives as novel antagonists of the prokaryotic proton-gated ion channel GLIC

…, J Marteaux, C Colas, C Van Renterghem…

Index: Bernini, Roberta; Barontini, Maurizio; Mosesso, Pasquale; Pepe, Gaetano; Willfoer, Stefan M.; Sjoeholm, Rainer E.; Eklund, Patrik C.; Saladino, Raffaele Organic and Biomolecular Chemistry, 2009 , vol. 7, # 11 p. 2367 - 2377

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Citation Number: 12

Abstract

... pLGICs constitute a large superfamily of receptors that are activated by a wide range of small organic compounds, notably ... between the ECD apex and the membrane.(1) It is formed by the A-, B-, and C-loops from one subunit (principal component) and the D-, E-, F-, and G ...