Abstract In this study, condensation of 2-amino-5-chlorobenzoic acid with benzoyl chloride afforded 2-benzamido-5-chloro benzoic acid which on cyclization with different primary amines yielded the corresponding 6-chloro-2-phenyl-3-substituted quinazolin-4 (3H)-ones (V1–V8). The reaction was monitored by thin layer chromatographic analysis. The structure of the synthesized compounds was confirmed by spectral studies and elemental analysis. ...