Lun Xu, Chao Wang, Ziwei Gao, Yu-Ming Zhao
Index: 10.1021/jacs.8b03015
Full Text: HTML
Herein, we report the first total syntheses of complex cephalotaxus diterpenoids cephanolide B and C from commercially available 5-bromo-2-methylanisole. Key to the success of this synthetic route is a palladium-catalyzed cascade cyclization reaction, which allowed us to efficiently forge the 6–5–6 cis-fused tricyclic ring systems found in the entire family of cephalotaxus diterpenoids. Additionally, site-selective late-stage sp3 C–H bond oxidation served as a key strategic element in the chemical synthesis of cephanolide C.
Mechanistic Study on Cu(II)-Catalyzed Oxidative Cross-Coupli...
2018-04-13 [10.1021/jacs.8b01896] |
Facile Multicomponent Polymerizations toward Unconventional ...
2018-04-13 [10.1021/jacs.8b01991] |
Disentangling Ligand Effects on Metathesis Catalyst Activity...
2018-04-13 [10.1021/jacs.8b02324] |
Metal Composition and Polyethylenimine Doping Capacity Effec...
2018-04-13 [10.1021/jacs.8b01252] |
Dynamic Covalent Metathesis in the C═C/C═N Exchange between ...
2018-04-13 [10.1021/jacs.8b01849] |
Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer
Copyright © 2024 ChemSrc All Rights Reserved