Highly selective monoacylation of symmetric diols catalyzed by metal sulfates supported on silica gel

T Nishiguchi, K Kawamine…

Index: Nishiguchi, Takeshi; Kawamine, Katsumi; Ohtsuka, Tomoko Journal of Organic Chemistry, 1992 , vol. 57, # 1 p. 312 - 316

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Citation Number: 50

Abstract

Several 1, n-diols, ranging from 1, a-ethanediol to 1, 16-hexadecanediol, were monoacylated with high selectivity by reaction with esters in the presence of metal sulfates or hydrogen sulfatea, like Ce (S04), and NaHS04, supported on silica gel. Symmetrical secondary diols were also selectively monoformylated, by reaction with ethyl formate. This method of selective esterification is simple and practical. The yield of monoester depends ...