Organic letters

Isoquinoline synthesis by heterocyclization of tosylmethyl isocyanide derivatives: total synthesis of mansouramycin B

A Coppola, D Sucunza, C Burgos, JJ Vaquero

Index: Naciuk, Fabricio F.; Milan, Julio C.; Andreao, Almir; Miranda, Paulo C.M.L. Journal of Organic Chemistry, 2013 , vol. 78, # 10 p. 5026 - 5030

Full Text: HTML

Citation Number: 12

Abstract

... Select a Journal or Book ... The isoquinoline core is an important structural motif that is found in many natural products,(1) pharmaceutically relevant molecules,(2) and organic materials.(3) Due to the significance of this core, diverse ... R 1, R 2, R 3, T (°C), yield a (%), compd. ...

 Related Synthetic Route

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~58%

~88%

~%

~%