Journal of Natural Products 2018-03-30

Total Synthesis of (±)-Minfiensine via a Formal [3+2] Cycloaddition

Chao Zhang, Wenzhi Ji, Yahu A. Liu, Chun Song, Xuebin Liao

Index: 10.1021/acs.jnatprod.7b00873

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Abstract

(±)-Minfiensine (1) was synthesized in 10 steps in 26% overall yield with the 1,2,3,4-tetrahydro-9a,4a-iminoethanocarbazole core constructed through a [3+2] cycloaddition reaction between indole and an azaoxyallylic cation.