Cell Chemical Biology 2018-04-05

Cellular Cyborgs: On the Precipice of a Drug Delivery Revolution

Song Ding, Colin P. O'Banion, Joshua G. Welfare, David S. Lawrence

Index: 10.1016/j.chembiol.2018.03.003

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Abstract

Cell-based drug delivery systems offer the prospect of biocompatibility, large-loading capacity, longin vivolifespan, and active targeting of diseased sites. However, these opportunities are offset by an array of challenges, including safeguarding the integrity of the drug cargo and the cellular host, as well as ensuring that drug release occurs at the appropriate time and place. Emerging strategies that address these, and related, issues, are described herein.