e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

6-Methylangelicins: a new series of potential photochemotherapeutic agents for the treatment of psoriasis

…, P Rodighiero, P Manzini, G Pastorini…

Index: Guiotto, A.; Rodighiero, P.; Manzini, P.; Pastorini, G.; Bordin, F.; et al. Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 959 - 967

Full Text: HTML

Citation Number: 111

Abstract

8-MOPc 736c 7.8 lC 0.128 c 3.10 X “According to McGhee and Von Hippel, ls n is defined here as the number of nucleotides occluded by one bound molecule of angelicin derivative. bl/n defines, according to McGhee and Von Hippel, the frequency of binding sites; in other words, it is the number of ligands bound per nucleotide and can be considered analogous to the “n “value obtained by the classic Scatchard method. 3l cAs reference compound; data ...

6-methyl-7-acetoxy-8-(2',3'-dibromopropyl)coumarin Structure

6-methyl-7-acet...

~45%

6,5'-dimethylangelicin Structure

6,5'-dimethylan...

7-Hydroxy-6-methyl-2H-1-benzopyran-2-one Structure

7-Hydroxy-6-met...

~%

6,5'-dimethylangelicin Structure

6,5'-dimethylan...

6-methyl-7-(allyloxy)coumarin Structure

6-methyl-7-(all...

~%

6,5'-dimethylangelicin Structure

6,5'-dimethylan...

6-methyl-7-hydroxy-8-allylcoumarin Structure

6-methyl-7-hydr...

~%

6,5'-dimethylangelicin Structure

6,5'-dimethylan...

6-methyl-7-acetoxy-8-allylcoumarin Structure

6-methyl-7-acet...

~%

6,5'-dimethylangelicin Structure

6,5'-dimethylan...

4,6-dimethyl-7-acetoxy-8-(2',3'-dibromopropyl)coumarin Structure

4,6-dimethyl-7-...

~37%

4,6,8-trimethylfuro[2,3-h]chromen-2-one Structure

4,6,8-trimethyl...

7-hydroxy-4,6-dimethylchromen-2-one Structure

7-hydroxy-4,6-d...

~%

4,6,8-trimethylfuro[2,3-h]chromen-2-one Structure

4,6,8-trimethyl...

4,6-dimethyl-7-(allyloxy)coumarin Structure

4,6-dimethyl-7-...

~%

4,6,8-trimethylfuro[2,3-h]chromen-2-one Structure

4,6,8-trimethyl...

4,6-dimethyl-7-hydroxy-8-allylcoumarin Structure

4,6-dimethyl-7-...

~%

4,6,8-trimethylfuro[2,3-h]chromen-2-one Structure

4,6,8-trimethyl...

4,6-dimethyl-7-acetoxy-8-allylcoumarin Structure

4,6-dimethyl-7-...

~%

4,6,8-trimethylfuro[2,3-h]chromen-2-one Structure

4,6,8-trimethyl...

5,6-di-methyl-7-acetoxy-8-(2',3'-dibromopropyl)coumarin Structure

5,6-di-methyl-7...

~41%

5,6,8-trimethylfuro[2,3-h]chromen-2-one Structure

5,6,8-trimethyl...

5,6-dimethyl-7-hydroxycoumarin Structure

5,6-dimethyl-7-...

~%

5,6,8-trimethylfuro[2,3-h]chromen-2-one Structure

5,6,8-trimethyl...

5,6-dimethyl-7-(allyloxy)coumarin Structure

5,6-dimethyl-7-...

~%

5,6,8-trimethylfuro[2,3-h]chromen-2-one Structure

5,6,8-trimethyl...

5,6-dimethyl-7-hydroxy-8-allylcoumarin Structure

5,6-dimethyl-7-...

~%

5,6,8-trimethylfuro[2,3-h]chromen-2-one Structure

5,6,8-trimethyl...

5,6-dimethyl-7-acetoxy-8-allylcoumarin Structure

5,6-dimethyl-7-...

~%

5,6,8-trimethylfuro[2,3-h]chromen-2-one Structure

5,6,8-trimethyl...

7-hydroxy-4,6-dimethylchromen-2-one Structure

7-hydroxy-4,6-d...

~%

4,6-dimethylfuro[2,3-h]chromen-2-one Structure

4,6-dimethylfur...

4,6-dimethyl-7-hydroxy-8-allylcoumarin Structure

4,6-dimethyl-7-...

~%

4,6-dimethylfuro[2,3-h]chromen-2-one Structure

4,6-dimethylfur...

2-(7-hydroxy-4,6-dimethyl-2-oxo-2H-chromen-8-yl)acetaldehyde Structure

2-(7-hydroxy-4,...

~%

4,6-dimethylfuro[2,3-h]chromen-2-one Structure

4,6-dimethylfur...

4,6-dimethyl-7-(allyloxy)coumarin Structure

4,6-dimethyl-7-...

~%

4,6-dimethylfuro[2,3-h]chromen-2-one Structure

4,6-dimethylfur...

((4,6-dimethyl-8-acetyl-7-coumarinyl)oxy)acetic acid Structure

((4,6-dimethyl-...

~64%

4,4',6-trimethylangelicin Structure

4,4',6-trimethy...

7-acetoxy-4,6-dimethyl benzopyran-2(H)-one Structure

7-acetoxy-4,6-d...

~%

4,4',6-trimethylangelicin Structure

4,4',6-trimethy...

4,6-dimethyl-7-hydroxy-8-acetylcoumarin Structure

4,6-dimethyl-7-...

~%

4,4',6-trimethylangelicin Structure

4,4',6-trimethy...

ethyl ((4,6-dimethyl-8-acetyl-7-coumarinyl)oxy)acetate Structure

ethyl ((4,6-dim...

~%

4,4',6-trimethylangelicin Structure

4,4',6-trimethy...

5,6-dimethyl-7-hydroxycoumarin Structure

5,6-dimethyl-7-...

~%

5,6-dimethylfuro[2,3-h]chromen-2-one Structure

5,6-dimethylfur...

2-(7-hydroxy-5,6-dimethyl-2-oxo-2H-chromen-8-yl)acetaldehyde Structure

2-(7-hydroxy-5,...

~%

5,6-dimethylfuro[2,3-h]chromen-2-one Structure

5,6-dimethylfur...

5,6-dimethyl-7-(allyloxy)coumarin Structure

5,6-dimethyl-7-...

~%

5,6-dimethylfuro[2,3-h]chromen-2-one Structure

5,6-dimethylfur...

5,6-dimethyl-7-hydroxy-8-allylcoumarin Structure

5,6-dimethyl-7-...

~%

5,6-dimethylfuro[2,3-h]chromen-2-one Structure

5,6-dimethylfur...

5,6-dimethyl-7-acetoxycoumarin Structure

5,6-dimethyl-7-...

~61%

8-acetyl-7-hydroxy-5,6-dimethylchromen-2-one Structure

8-acetyl-7-hydr...