Synlett

1, 5-Diketone synthesis promoted by barium hydride or barium alkoxides

H Takahashi, T Arai, A Yanagisawa

Index: Takahashi, Hiroshi; Arai, Takayoshi; Yanagisawa, Akira Synlett, 2006 , # 17 p. 2833 - 2835

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Citation Number: 9

Abstract

Abstract A tandem cross-coupling reaction of ketones with aldehydes has been achieved using barium hydride or isopropoxide as a promoter, in which barium enolates are generated in situ and then three successive reactions (aldol reaction-β-elimination-Michael addition) follow; this one-pot process is effective for obtaining symmetrical 1, 5-diketones in good yields.