Tetrahedron

Application of palladium-catalyzed Pd–aryl/P–aryl exchanges: preparation of functionalized aryl phosphines by phosphination of aryl bromides using …

FY Kwong, CW Lai, M Yu, KS Chan

Index: Kwong, Fuk Yee; Lai, Chi Wai; Yu, Michael; Chan, Kin Shing Tetrahedron, 2004 , vol. 60, # 26 p. 5635 - 5645

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Citation Number: 31

Abstract

Palladium-catalyzed Pd–aryl/P–aryl interchange reaction was applied in the synthesis of various functionalized arylphosphines. This phosphination used inexpensive, readily available and air stable triarylphosphines as the phosphinating agents. Broad functional groups were compatible including keto, aldehyde, ester, nitrile, ether, chloride, pyridyl and thiophenyl groups. Halides were found to be good promoter for the rates and yields of the ...